Bettencourt F.: Effects of Class IV Laser in Knee Osteoarthritis: A Randomized Control Trial
Class IV laser treatment was found to be an effective modality in reducing knee pain in patients with osteoarthritis. The laser group showed over 44% improvement in pain reduction, whereas the placebo control group displayed no significant difference in pain perception following the treatments.
Marshall R.P., Vlková K.: Spectral Dependence of Laser Light on Light-tissue Interactions and its Influence on Laser Therapy: An Experimental Study
The experiment showed that longer wavelengths lead to decreasing energy absorption and refraction index in the melanin, as well as a reduction of hemoglobin energy absorption. We conclude that reflection and melanin absorption are negligible for wavelengths higher than 1000 nm due to the ability to penetrate higher amounts of energy into the tissue.
